Dermatology

Treatment of toxic epidermal necrolysis in AIDS with intravenous immunoglobulins.

Clin Exp Dermatol. 2003 May;28(3):269-71.
 
Tan A, Tan HH, Lee CC, Ng SK.

National Skin Centre, Singapore. audreytan@nsc.gov.sg

Individuals with AIDS are at higher risk of developing severe cutaneous adverse drug reactions. We report two AIDS patients with drug-induced toxic epidermal necrolysis (TEN). The suspected drugs were discontinued. Both patients were treated with intravenous human immunoglobulins at a dose of 1 g/kg body weight per day for two consecutive days and both experienced a good outcome. Intravenous immunoglobulin potentially lowers the morbidity and mortality of TEN and shortens the duration of the patient's hospitalization.

Publication Types:
  • Case Reports

PMID: 12780710 [PubMed - indexed for MEDLINE]
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