Hematology

Remission of severe, intractable autoimmune haemolytic anaemia following matched unrelated donor transplantation.

Bone Marrow Transplant. 2001 Oct;28(8):791-3.  
 
Pratt G, Kinsey SE.

Yorkshire Regional Centre for Paediatric Oncology and Haematology, St James's University Hospital, Leeds, UK.

Immune-mediated haemolytic anaemia presenting post allogeneic bone marrow transplantation is often alloimmune in origin due to ABO or minor red cell incompatibilities. Autoimmune haemolytic anaemia is also recognised, is frequently difficult to treat and overall prognosis is often poor, usually from associated problems. Here, we present a case report of autoimmune haemolysis presenting in an 8-year-old boy 6 months post allogeneic bone marrow transplant requiring 4 years of immunosuppressive therapy before remission of haemolysis. This case report highlights the fact that it is possible for haemolysis to resolve post transplant even after years of immunosuppressive therapy.

Publication Types:
  • Case Reports

PMID: 11781633 [PubMed - indexed for MEDLINE]
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