Neurology

Multifocal motor neuropathy presenting as chronic progressive proximal leg weakness.

 

Neuromuscul Disord. 2004 Jun;14(6):380-2.  
 

Maurer M, Stoll G, Toyka KV.

Department of Neurology, University of Wurzburg, Josef-Schneider-Str. 11, 97080 Wurzburg, Germany. maeurer_m@klinik.uni-wuerzburg.de

We report on a 47-year-old man with a 12-year history of progressive and ultimately severe proximal weakness of his right lower limb. Motor conduction block at the unaffected tibial nerve and positive IgM antibodies against GM1 gangliosides lead us to suggest a diagnosis of oligosymptomatic multifocal motor neuropathy. He rapidly responded to intravenous immunoglobulins, with complete remission lasting 4 weeks, and had a repeated treatment response to intravenous immunoglobulins during subsequent exacerbations. The proximal involvement may represent another unusual clinical manifestation of multifocal motor neuropathy. Copyright 2004 Elsevier B.V.

Publication Types:
  • Case Reports

PMID: 15145341 [PubMed - indexed for MEDLINE]
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