People donate plasma for many reasons. Research shows those motivations are both practical and deeply personal.
When asked, “Why did you donate plasma?”, participants in a 2023 study by PPTA were able to select multiple responses. Across all donation frequency groups and for both men and women, one reason stood out most consistently: interest in extra income. Nearly nine in ten donors — regardless of sex or donation frequency — cited compensation as a motivating factor.
But the data also makes one thing clear: plasma donation is about much more than money.
For both male and female donors, the second most frequently selected reason was “My plasma will save lives.” This highlights a strong awareness among donors of the critical role plasma plays in creating life-saving therapies for patients with rare and serious conditions.
Altruistic motivations featured prominently as well. Many donors reported that donating plasma “feels like the right thing to do” and that treating rare diseases is important to them. While the order of these motivations varied slightly between men and women, both groups consistently ranked them among their top reasons for donating.
Additional responses, such as donating because it feels good personally or because friends and family also donate, further reinforce that plasma donation is influenced by a mix of financial, emotional, and social factors.
Taken together, the findings show that plasma donors are motivated by a combination of practical needs and a genuine desire to help others. Understanding this full picture is essential for recognizing donors’ contributions, supporting positive donor experiences, and ensuring a stable plasma supply for the patients who rely on these medicines to live healthy, fulfilling lives.



